Economic Evaluation of Genomic Technologies: Methods and Guidance


  • Christopher McCabe, PhD, Research Director, Capitol Health Endowed Chair, Department of Emergency Medicine, University of Alberta, Edmonton
  • Brenda Wilson, MB ChB, MSc, MRCP(UK), FFPH, Professor, Department of Epidemiology and Community Medicine, University of Ottawa
  • The Canadian Agency for Drugs and Technologies in Health (CADTH) delivers reliable, evidence-based information about the effectiveness and efficiency of drugs and other health technologies through a variety of products and services. CADTH guidelines for economic evaluation are a widely known and cited source for the evaluation of health technologies.

    The guidelines are currently being updated and will include a chapter intended to provide specific guidance on the methods used to conduct high-quality economic evaluations of genomic technologies. The evaluation of these rapidly developing and potentially disruptive genomic technologies present special challenges because understanding their value may require, among other things, a specialized knowledge of related laboratory work and services, clinical diagnostics, and genomic therapies.

    This workshop aims to engage experts in clinical research, lab research, and program development who are interested in learning about current economic evaluation methods and who can help to inform the development of guidelines for the economic evaluation of genomic technologies.


    • Share the current guidance for the economic evaluation of genomic technologies (including diagnostics)
    • Identify major issues in economic evaluation for genomic technologies and propose potential solutions
    • Participate in, and assist with, the translational work and promotion of the guidance within various professional communities.

    Preliminary Agenda

    12:00-12:30    Introduction and outcomes – Chris McCabe
              - Session Overview and Introductions – Mike Tomlinson, facilitator

    12:30-1:15     Session 1: Current methods of appraisal of diagnostic technologies
              - Presentation: Prof. Chris McCabe, University of Alberta

    1:15-2:15       Session 2: A Conceptual Model for the Evaluation of Genomic Technologies
              - Presentation/Q&A. Presenter TBA

    2:15-2:35       Break

    2:35-3:30       Session 3: Value Issues in Genomic Technologies
              - Presenter: Dr. Brenda Wilson, University of Ottawa

    3:30-4:30       Session 4: Identification of key issues – Facilitated discussion
              - Small group work to determine top issues

    4:30-4:50       Break

    4:50-6:20       Session 5: Identification of potential solutions on key issues – facilitated process
              - Problem statements, current activities, and identifying experts to support the guidance work of the Chapter Writing Group

    6:20-6:45       Plenary Summary – Chris McCabe

    6:45 -7:00      Closing Remarks and Next Steps – Chris McCabe

    The number of participants will be limited to: 30

    As space is limited, please register now by contacting Ken Bond (Director, Strategic Initiatives) at

    For more information about this workshop, please contact Ken Bond.